SWITCHING TO A WESTERN DIET TRIGGERS INFLAMMATION AND WEAKENS IMMUNITY

A switch of just two weeks from a traditional African diet to a Western diet causes inflammation, reduces the immune response to pathogens, and activates processes associated with lifestyle diseases. Conversely, an African diet rich in vegetables, fiber, and fermented foods has positive effects. This study, published in Nature Medicine, highlights the significant impact of diet on the immune system and metabolism.

Lifestyle diseases such as cardiovascular diseases, diabetes, and chronic inflammatory conditions are surging across Africa, posing a growing challenge to healthcare systems throughout the continent. Increasing economic development, urbanization and wider availability of processed foods have accelerated the adoption of Western eating habits in Africa. To understand the health consequences of this shift, researchers from Radboud university medical center and KCMC University in Tanzania have studied the effects of such dietary changes on health.

Lifestyle diseases

Seventy-seven healthy men from Tanzania, both urban and rural residents, participated in the study. Some participants who traditionally ate an African diet switched to a Western diet for two weeks, while others who ate a Western diet adopted a traditional African diet. A third group consumed a fermented banana drink daily. As a control, ten participants maintained their usual diet. The researchers comprehensively analyzed the function of the immune system, blood inflammation markers, and metabolic processes at baseline, after the two-week intervention, and again four weeks later.

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2025-04-03T13:15:53Z